Pan-retroviral nucleocapsid-mediated phase separation

Pan-retroviral nucleocapsid-mediated phase separation regulates genomic RNA positioning and trafficking. Membraneless organelles are formed by liquid-liquid phase separation of disordered protein prion-like domains (PrLDs), RNA-binding motifs (RRMs) & Zinc fingers (ZnFs) Elie Dolgin. Nature. 2018 Mar 15;555(7696):300-302. Verdile V. et al. Front Genet. 2019 Mar 22;10:173. Wang J. et al. Cell

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Separation-Individuation | Encyclopedia.com

Separation-Individuation. Margaret Mahler (1897–1986) represents a group of ego psychologists whose interest focuses on the development of psychic structures, as outlined in Sigmund Freud's ([1923] 1990) structural theory, the id, ego, and superego. Mahler's interest in the developing ego centered on its development within the context of object relationships.

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Richard Youngs | Discography | Discogs

Richard Youngs is a British musician with a prolific and diverse output, including many collaborations. Based in Glasgow since the early 1990s, his extensive back catalogue of solo and collaborative work formally begins with Advent, first issued in 1990. He plays many instruments, most commonly choosing the guitar, but he has been known to use a wide variety of other instruments including the

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Transcription Factors Activate Genes through the

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains. Cell ( IF 36.216) Pub Date : 2018-11-15, DOI: 10.1016/j.cell.2018.10.042 Ann Boija,Isaac A Klein,Benjamin R Sabari,Alessandra Dall'Agnese,Eliot L Coffey,Alicia V Zamudio,Charles H Li,Krishna Shrinivas,John C Manteiga,Nancy M Hannett,Brian J Abraham,Lena K Afeyan,Yang E Guo,Jenna K

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Separation Anxiety Disorder in Children - WebMD

Separation anxiety is normal in very young children (those between 8 and 14 months old). Kids often go through a phase when they are "clingy" and afraid of unfamiliar people and places. When this

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Nucleation of Supercooled Water - video dailymotion

28/08/2015· Browse more videos. Playing next. 0:16

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Mechanism of DNA‐Induced Phase Separation for

Phase separation of proteins/nucleic acids to form non‐membrane organelles is crucial in cellular gene‐expression regulation. However, little is known about transcriptional regulator phase separation and the underlying molecular mechanism. Vernalization 1 (VRN1) encodes a crucial transcriptional repressor involved in plant vernalization that contains two B3 DNA‐binding domains connected

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Transcription regulation enters a new phase

Figure 1 | Phase separation in transcription regulation. a, The P-TEFb complex consists of two proteins, CCNT1 and CDK9.Lu et al. 1 have identified a histidine-rich domain (HRD) in CCNT1 that

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Stages of Divorce: What Do Individuals Really Go

In many ways divorce is like going through the death of a loved one, involving loss and grief. It changes the structure of the family forever. Divorce causes the loss of hopes and dreams of what marriage and a family are supposed to be.. There is no one experience of divorce. Changing status from being married to being single can present varied difficulties in emotional adjustments for people

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Role of nuclear RNA in regulating chromatin

This suggests that its phase separation properties are expected to be dependent on both RNA and ATP. While far from being characterised in full, we hypothesise that the phase separation phenomenology of RNA-binding proteins with ATPase domains will be more pervasive than those of other non-ATP-consuming proteins such as HP1. The

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A Phase Separation Model for Transcriptional Control

Phase-separated multi-molecular assemblies provide a general regulatory mechanism to compartmentalize biochemical reactions within cells. We propose that a phase separation model explains established and recently described features of transcriptional control. These features include the formation of super-enhancers, the sensitivity of super-enhancers to perturbation, the transcriptional

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14 SEPARATION TECHNIQUES

14 SEPARATION TECHNIQUES 14.1 Introduction The methods for separating, collecting, and detecting radionuclides are similar to ordinary analytical procedures and employ many of the chemical and physical principles that apply to their nonradioactive isotopes. However, some important aspects of the behavior of radionuclides are significantly different, resulting in challenges to the radiochemist

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Archive ouverte HAL - Phase Separation in the Two

Phase Separation in the Two-Dimensional Bosonic Hubbard Model with Ring Exchange . Valery Rousseau 1 G. George Batrouni 2 Richard Scalettar 1 Détails. 1 Department of Physics [Davis] 2 INLN - Institut Non Linéaire de Nice Sophia-Antipolis

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Approach | Dewpoint

These scientists realized that P granules behave like liquid droplets that form by phase separation (think of oil they are liquid-like and form by phase separation. Inspired by the work of Tony and his colleagues, Richard Young, Phillip Sharp, and Arup Chakraborty at MIT applied these approaches to the study of gene expression, similarly shedding light on many important questions in gene

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PHASE SEPARATION AND CRYSTALLIZATION OF COMPLEX

PHASE SEPARATION AND CRYSTALLIZATION OF COMPLEX BOROSILICATE MELTS FOR GLASS-CERAMIC WASTE FORMS Fuel Cycle Research and Development Richard K. Brow Missouri Universityof Science and Technology Kimberly Gray, Federal POC John Vienna, Technical POC Project No. 15-8112. Nuclear Energy University Program Project 15 -8112 . PHASE SEPARATION AND CRYSTALLIZATION OF COMPLEX BOROSILICATE MELTS

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Vapor–liquid equilibrium - Wikipedia

At any given temperature where both phases are present, vapor with a certain mole fraction is in equilibrium with liquid with a certain mole fraction. The two mole fractions often differ. These vapor and liquid mole fractions are represented by two points on the same horizontal isotherm (constant T ) line. When an entire range of temperatures vs. vapor and liquid mole fractions is graphed, two

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Richard Young - IMDb

Richard Young, Actor: Indiana Jones and the Last Crusade. Richard Young (born December 17, 1955) is an American actor, independent filmmaker, screenwriter, photographer, and artist. Active from the early 1970s, he gained prominence starring

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Targeting liquid-liquid phase separation in

Targeting liquid-liquid phase separation in pancreatic cancer. Background: Accumulated evidence suggests a critical role of protein-mediated liquid-liquid phase separation (LLPS) in many key biological processes through organization of membrane-less compartments. However, the pathological role of protein-mediated LLPS remains elusive and it is unknown whether protein-mediated LLPS contributes

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A phase separation model predicts key features of

23/03/2017· Our phase separation model suggest that this is because stimulation by TNFα-led to modifications that change the valency of interacting components, and for SEs, phase separation occurs sharply above a lower value of valency compared to typical enhancers, thus resulting in enhanced recruitment of interacting components such as BRD4 (Figure 2C).

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Hyman Lab | Max Planck Institute of Molecular Cell

An interview with Tony about Phase Transitions and Disease. Phase separation in cell polarity: Saha et al, Cell 2016. Encouraging Innovation, iBiology.org. The genetics linking temperature and fertility in worms: Leaver et al, Biology Open 2016. Cell PaperFlick on Phase Transitions in Disease

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